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Vol.  27, suppl. 1, 2009    article (references)    article (pdf 324 kb)      ibd and ibs: novel mechanisms and future practice. Editor(s): travis s. P. viagra uses side effects L. tesco to sell half-price viagra (oxford), spiller r. C. (nottingham), colombel j. -f. (lille), holzer p. (graz) paper collagenous and lymphocytic colitis: systematic review and update of the literature f. Temmerman, f. Baert department of internal medicine, section of gastroenterology, h. Hart ziekenhuis roeselare, menen, belgium address of corresponding author dig dis 2009;27 (suppl. viagra without prescription 1):137-145 (doi: 10. 1159/000268134)    key words microscopic colitis collagenous colitis lymphocytic colitis budesonide    abstract collagenous and lymphocytic colitis are well-described conditions causing chronic watery diarrhoea. viagra coupon A peak incidence from 60 to 70 years of age with a female predominance mainly in collagenous colitis is observed. viagra generic Both conditions are characterised by a (near) normal colonoscopy, but with specific histologic findings on colonic biopsies. generic viagra without prescription Histopathologically, both conditions are characterised by distinct epithelial abnormalities and a dense lymphoplasmocytic infiltrate. generic viagra canada Distinct features consist of a characteristic collagen band deposition in the subepithelial layer in collagenous colitis and a markedly increased number of intra-epithelial lymphocytes in lymphocytic colitis. Although most cases are idiopathic, certain drugs can induce microscopic colitis. In addition, either condition can be associated with coeliac disease. For a long time patients with microscopic colitis were treated with non-specific anti-diarrhoeal agents, anti-inflammatory agents such as mesalazine, or systemic steroids, but with disappointing results. buy viagra without prescription Bismuth subsalicylate was reported to be effective in a small controlled series of patients with collagenous colitis. Now, randomised controlled trials have shown the effectiveness of budesonide over placebo in collagenous colitis and more recently in lymphocytic colitis. The histologic response is variable, but a decrease in the subepithelial collagen layer and a decrease in the lymphoplasmocytic infiltrate in the lamina propria is observed in about half of the patients. cheap viagra online in the uk In general, patients.